Three neighboring genes interact with the Broad-Complex and the Stubble-stubbloid locus to affect imaginal disc morphogenesis in Drosophila.

doi:10.1093/genetics/127.4.747

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Article

Three neighboring genes interact with the Broad-Complex and the Stubble-stubbloid locus to affect imaginal disc morphogenesis in Drosophila.

Genetics - 1 Apr 1991

Gotwals P J, Fristrom J W

Abstract excerpt

The Broad-Complex (BR-C) is a complex regulatory locus at 2B-5 on the X chromosome of Drosophila melanogaster. The wild-type BR-C products are apparent transcription factors necessary for imaginal disc morphogenesis. Alleles of the Stubble-stubbloid (Sb-sbd) locus at 89B9-10 act as dominant enhancers of broad alleles of the BR-C. Sb-sbd wild-type products are necessary for appendage elongation. We report, here,...

Topics

Alleles
Animals
Cell Differentiation
Chromosome Mapping
Crosses, Genetic
Drosophila melanogaster
Enhancer Elements, Genetic
Epithelial Cells
Gene Expression Regulation
Genes, Dominant
Genes, Lethal

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Genes, Recessive

Genes, Regulator

Genetic Complementation Test

Genetic Variation

Genotype

Morphogenesis

Mutation

Source

Open in PubMed Open full text

Identifiers

PMID: 1903118
DOI: 10.1093/genetics/127.4.747
PMCID: PMC1204402

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1903118-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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