Article
Implications of the Tribolium Deformed mutant phenotype for the evolution of Hox gene function.
Proceedings of the National Academy of Sciences of the United States of America - 25 Apr 2000
Brown S, DeCamillis M, Gonzalez-Charneco K, Denell M, Beeman R, Nie W, Denell R
Abstract excerpt
Among insects, the genetic regulation of regional identities in the postoral head or gnathal segments (mandibular, maxillary, and labial) is best understood in the fly Drosophila melanogaster. In part, normal gnathal development depends on Deformed (Dfd) and Sex combs reduced (Scr), genes in the split Drosophila homeotic complex. The gnathal segments of Dfd and Scr mutant larvae are abnormal but not homeotically...
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