Article
Activation of Gal4p by galactose-dependent interaction of galactokinase and Gal80p.
Science (New York, N.Y.) - 14 Jun 1996
Zenke F T, Engles R, Vollenbroich V, Meyer J, Hollenberg C P, Breunig K D
Abstract excerpt
Yeast galactokinase (Gal1p) is an enzyme and a regulator of transcription. In addition to phosphorylating galactose, Gal1p activates Gal4p, the activator of GAL genes, but the mechanism of this regulation has been unclear. Here, biochemical and genetic evidence is presented to show that Gal1p act...
Topics
- Amino Acid Sequence
- Coenzymes
- DNA-Binding Proteins
- Fungal Proteins
- Galactokinase
- Galactose
- Kluyveromyces
- Molecular Sequence Data
- Mutation
- Repressor Proteins
- Saccharomyces cerevisiae
- Saccharomyces cerevisiae Proteins
- Signal Transduction
- Transcription Factors