Article
Characterization of sua7 mutations defines a domain of TFIIB involved in transcription start site selection in yeast.
The Journal of biological chemistry - 2 Dec 1994
Pinto I, Wu W H, Na J G, Hampsey M
Abstract excerpt
The SUA7 gene of Saccharomyces cerevisiae encodes the general transcription factor TFIIB. SUA7 was identified based on the ability of mutations at this locus to shift transcription start site selection at the cyc1 gene downstream of normal. Here, we report the nature of these mutations; the sua7-1 and sua7-2 alleles encode identical E62K replacements, and sua7-3 encodes an R78C replacement. Both Glu-62 and Arg-78...
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