Multiple mitochondrial DNA deletions in sporadic inclusion body myositis: A study of 56 patients

Abstract excerpt

Inclusion body myositis, a chronic inflammatory disorder, is the most common cause of myopathy in adults over the age of 50. Diagnosis is based on clinical features and distinctive morphological findings by both light and electron microscopy. The causes of inclusion body myositis are still unknown. Ultrastructural mitochondrial changes and ragged-red fibers are common in patients with sporadic inclusion body...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Genetic Neurodegenerative Diseases
• Share to Inflammatory Myopathies and Dermatomyositis
• Share to Nuclear Structure and Function