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Article

The newly identified yeast GRD genes are required for retention of late-Golgi membrane proteins.

Molecular and cellular biology - 1 Jun 1996

Nothwehr S F, Bryant N J, Stevens T H

Abstract excerpt

Processing of A-ALP, a late-Golgi membrane protein constructed by fusing the cytosolic domain of dipeptidyl aminopeptidase A to the transmembrane and lumenal domains of alkaline phosphatase (ALP), serves as a convenient assay for loss of retention of late-Golgi membrane proteins in Saccharomyces cerevisiae. In this study, a large group of novel grd (for Golgi retention defective) yeast mutants, representing 18...

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Identifiers

PMID: 8649377
DOI: 10.1128/MCB.16.6.2700
PMCID: PMC231260

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