Article
Development of allergy to laboratory animals is associated with particular Gm and HLA genes.
International archives of allergy and immunology - 1 May 1996
Oxelius V A, Sjöstedt L, Willers S, Löw B
Abstract excerpt
To find out whether IgG genes are involved in atopy we studied 26 of 101 laboratory technicians who had developed laboratory animal allergy (LAA). The genes for the constant region of the heavy chains of IgG subclasses were analyzed by serum Gm allotypes, representing products on allelic level of the IGHCG1, IGHCG2 and IGHCG3 on chromosome 14q32. There was a significantly increased frequency of the...
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