Article
Susceptibility to coeliac disease in Tunisian children and GM immunoglobulin allotypes.
European journal of immunogenetics : official journal of the British Society for Histocompatibility and Immunogenetics - 1 Aug 1999
Bouguerra F, Dugoujon J M, Babron M C, Greco L, Khaldi F, Debbabi A, Bennaceur B, Clerget-Darpoux F
Abstract excerpt
Coeliac disease is a malabsorption disorder of the small intestine resulting from ingestion of gluten. The immunogenetic component is clearly demonstrated by the association of the disease with human leukocyte antigens (HLA). Among other candidate genes are the GM allotypes, which are the markers of the constant parts of heavy chains of the subclasses IgG1, IgG2 and IgG3. GM immunoglobulin allotypes have been...
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