Gm allotype genes and gene dosage affecting both IgG subclass and IgE levels in atopic patients.

doi:10.1159/000235090

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Article

Gm allotype genes and gene dosage affecting both IgG subclass and IgE levels in atopic patients.

International archives of allergy and applied immunology - 1 Jan 1990

Oxelius V A

Abstract excerpt

The imbalanced IgG subclass levels of 50 atopic patients with IgE greater than 600 kU/l reflected the Gm expression of the patients. IgG1 was significantly increased but only in patients with the phenotypes Gm(f,f,n,n) and Gm(a,a,'',''). The typical IgG4 increase was found in the most frequent Gm...

Topics

Adolescent
Adult
Child
Child, Preschool
Female
Genes, Immunoglobulin
Heterozygote
Homozygote
Humans
Hypersensitivity, Immediate
Immunoglobulin E
Immunoglobulin G
Immunoglobulin Gm Allotypes
Male
Phenotype

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