Article
Allotype-associated differences in concentrations of human IgG subclasses.
Journal of clinical immunology - 1 Jan 1991
Sarvas H, Rautonen N, Mäkelä O
Abstract excerpt
The concentrations of seven immunoglobulin isotypes (IgA, IgE, IgM, IgG1, IgG2, IgG3, and IgG4) were measured in the sera of 207 Finnish blood donors, and they were allotyped with anti-Gm antibodies: anti-f, anti-a, anti-x, and anti-n. The above population could be divided into 12 phenotypes, and significant differences in isotype concentrations between different phenotypes were observed. They are best explained...
Topics
- Alleles
- Humans
- Immunoglobulin G
- Immunoglobulin Gm Allotypes
- Immunophenotyping
- Isoantibodies
