Article
HLA associations with occupational sensitization to rat lipocalin allergens: a model for other animal allergies?
The Journal of allergy and clinical immunology - 1 Apr 2003
Jeal Hayley, Draper Adrian, Jones Meinir, Harris Jessica, Welsh Ken, Taylor Anthony Newman, Cullinan Paul
Abstract excerpt
BACKGROUND: Laboratory animal allergy is a common occupational health problem affecting between 11% and 44% of exposed researchers. Allergy to rats and mice is most common, probably because these are the animals most frequently used. OBJECTIVE: We hypothesized that HLA class II molecules, involved in the presentation of allergen to the T cell and likely candidates for controlling the immune response, might be...
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