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Article

An increased risk of Crohn's disease in individuals who inherit the HLA class II DRB3*0301 allele.

Proceedings of the National Academy of Sciences of the United States of America - 14 May 1996

Forcione D G, Sands B, Isselbacher K J, Rustgi A, Podolsky D K, Pillai S

Abstract excerpt

The role of inflammatory T cells in Crohn's disease suggests that inherited variations in major histocompatibility complex (MHC) class II genes may be of pathogenetic importance in inflammatory bowel disease. The absence of consistent and strong associations with MHC class II genes in Caucasian patients with inflammatory bowel disease probably reflects the use of less precise typing approaches and the failure to...

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Identifiers

PMID: 8643533
DOI: 10.1073/pnas.93.10.5094
PMCID: PMC39412

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Source receipt: pubmed, retrieved 7 Sept 2026.

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An increased risk of Crohn's disease in individuals who inherit the HLA class II DRB3*0301 allele.PMID 8643533Read ↗

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