Article
The distribution of HLA-DRB alleles in ulcerative colitis patients in Turkey.
European journal of immunogenetics : official journal of the British Society for Histocompatibility and Immunogenetics - 1 Aug 1998
Uyar F A, Imeryüz N, Saruhan-Direskeneli G, Ceken H, Ozdoğan O, Sahin S, Tözün N
Abstract excerpt
Recently described distinct associations of HLA class II genes with ulcerative colitis (UC) suggest a genetic heterogeneity for disease susceptibility. In this study, HLA-DRB alleles of UC patients (n = 59) from Turkey were investigated and compared with healthy controls (n = 244). Using molecular genotyping by polymerase chain reaction (PCR) and sequence-specific oligonucleotide hybridization, we have shown a...
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