Article
A quantitative trait locus in major histocompatibility complex determining latent period of mouse lymphomas.
Japanese journal of cancer research : Gann - 1 Apr 1996
Kamoto T, Shisa H, Pataer A, Lu L, Yoshida O, Yamada Y, Hiai H
Abstract excerpt
The effects of two host genes on retrovirus-induced murine lymphoma were evaluated by studying 114 F2 intercross mice between SL/Kh and AKR/Ms mice. Out of 47 T-lymphoma-bearing F2 mice, 45 had the AKR-derived dominant allele at Tism-1. The length of the lymphoma latent period was not related to type of tumor. Instead, it was significantly shortened by a recessive SL/Kh-derived allele at a major...
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