Article
Principal component analysis of quantitative trait loci for immune response to adenovirus in mice.
Hereditas - 1 Dec 2006
Musani Solomon K, Zhang Huang-Ge, Hsu Hui-Chen, Yi Nengjun, Gorman Bernard S, Allison David B, Mountz John D
Abstract excerpt
Data on the duration of transgene expression in the liver, the presence of cytotoxic T lymphocytes (CTLs) against adenovirus, and serum cytokines from 18 strains of C57BL/6 x DBA/2 (B x D) recombinant inbred mice were analyzed. Our aim was to detect quantitative trait loci (QTLs) that may have causal relationship with the duration of adenovirus-mediated transgene expression in the liver. Information from...
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