Article
A Legionella pneumophila gene that promotes hemin binding.
Infection and immunity - 1 Mar 1996
O'Connell W A, Hickey E K, Cianciotto N P
Abstract excerpt
The ability to bind and utilize hemin is a trait common to many human pathogens. Nevertheless, the relationship between Legionella pneumophila, the agent of Legionnaires' disease, and hemin has received little attention. Thus, we explored the capacity of a virulent, serogroup 1 strain of L. pneumophila to bind hemin and use it as an iron source. Hemin, but not protoporphyrin IX, restored bacterial growth in...
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