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Article

Use of heme compounds as iron sources by pathogenic neisseriae requires the product of the hemO gene.

Journal of bacteriology - 1 Jan 2000

Zhu W, Hunt D J, Richardson A R, Stojiljkovic I

Abstract excerpt

Heme compounds are an important source of iron for neisseriae. We have identified a neisserial gene, hemO, that is essential for heme, hemoglobin (Hb), and haptoglobin-Hb utilization. The hemO gene is located 178 bp upstream of the hmbR Hb receptor gene in Neisseria meningitidis isolates. The product of the hemO gene is homologous to enzymes that degrade heme; 21% of its amino acid residues are identical, and 44%...

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Identifiers

PMID: 10629191
DOI: 10.1128/JB.182.2.439-447.2000
PMCID: PMC94294

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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