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Burkholderia pseudomallei Known Siderophores and Hemin Uptake Are Dispensable for Lethal Murine Melioidosis

26 Jun 2012

Abstract excerpt

Burkholderia pseudomallei is a mostly saprophytic bacterium, but can infect humans where it causes the difficult-to-manage disease melioidosis. Even with proper diagnosis and prompt therapeutic interventions mortality rates still range from >20% in Northern Australia to over 40% in Thailand. Surprisingly little is yet known about how B. pseudomallei infects, invades and survives within its hosts, and virtually...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 22745846
DOI: 10.1371/journal.pntd.0001715

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