Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Disorders of glycoprotein degradation.

Journal of inherited metabolic disease - 1 Jan 1990

Cantz M, Ulrich-Bott B

Abstract excerpt

The intracellular degradation of glycoproteins occurs predominantly in the lysosomes through the concerted action of proteases and glycosidases. Genetic defects in any of the enzymes cleaving the oligosaccharide side chains lead to specific diseases because of an excessive lysosomal accumulation of partially degraded material, mostly oligosaccharides. This paper presents an overview of the biochemistry and the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carbohydrate Conformation
Share to Carbohydrate Sequence
Share to Glycoproteins

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Hydrolysis

Share to Molecular Sequence Data

Share to Mutation

Source

Identifiers

PMID: 2122119
DOI: 10.1007/BF01799510

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Disorders of glycoprotein degradation.PMID 2122119Read ↗

Glycoprotein lysosomal storage disorders: alpha- and beta-mannosidosis, fucosidosis and alpha-N-acetylgalactosaminidase deficiency.Semantic proximity Read ↗

Lysosomal diseases: biochemical pathways and investigations.Semantic proximity Read ↗

The genetics of sphingolipid hydrolases and sphingolipid storage diseases.Semantic proximity Read ↗

Alterations in membrane trafficking and pathophysiological implications in lysosomal storage disorders.Semantic proximity Read ↗

Neu4, a novel human lysosomal lumen sialidase, confers normal phenotype to sialidosis and galactosialidosis cells.Semantic proximity Read ↗

Recent advances in the biochemistry and genetics of sphingolipidoses.Semantic proximity Read ↗

[Sialic acid storage disease].Semantic proximity Read ↗

Aspartylglycosaminuria: protein chemistry and molecular biology of the most common lysosomal storage disorder of glycoprotein degradation.Semantic proximity Read ↗

The lysosomal storage disorders mucolipidosis type II, type III alpha/beta, and type III gamma: Update onGNPTABandGNPTGmutationsSemantic proximity Read ↗

Lysosomal high molecular weight multienzyme complex.Semantic proximity Read ↗

Novel mutations in lysosomal neuraminidase identify functional domains and determine clinical severity in sialidosis.Semantic proximity Read ↗

Maturation of Lysosomal α-Galactosidase A and Implications for Fabry Disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.