Article
Aspartylglycosaminuria: protein chemistry and molecular biology of the most common lysosomal storage disorder of glycoprotein degradation.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 1 Oct 1993
Mononen I, Fisher K J, Kaartinen V, Aronson N N
Abstract excerpt
Aspartylglycosaminuria (AGU) (McKusick 20840) is the most common disorder of glycoprotein degradation caused by the failure of lysosomes to digest the protein-to-carbohydrate linkage of Asn-linked glycoproteins. During the past few years there has been significant progress in our understanding of...
Topics
- Acetylglucosamine
- Amino Acid Sequence
- Aminolevulinic Acid
- Animals
- Aspartylglucosylaminase
- Base Sequence
- Biological Evolution
- Carbohydrate Sequence
- DNA, Complementary
- Glycoproteins
- Humans
- Lysosomal Storage Diseases
- Molecular Sequence Data
- Mutation