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Article

Aspartylglycosaminuria: protein chemistry and molecular biology of the most common lysosomal storage disorder of glycoprotein degradation.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 1 Oct 1993

Mononen I, Fisher K J, Kaartinen V, Aronson N N

Abstract excerpt

Aspartylglycosaminuria (AGU) (McKusick 20840) is the most common disorder of glycoprotein degradation caused by the failure of lysosomes to digest the protein-to-carbohydrate linkage of Asn-linked glycoproteins. During the past few years there has been significant progress in our understanding of both the protein chemistry and molecular biology of glycosylasparaginase (EC 3.5.1.26) as well as the molecular...

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PMID: 8405810
DOI: 10.1096/fasebj.7.13.8405810

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