Article
Resistance to activated protein C in an unselected population of patients with pulmonary embolism.
Lancet (London, England) - 18 May 1996
Desmarais S, de Moerloose P, Reber G, Minazio P, Perrier A, Bounameaux H
Abstract excerpt
BACKGROUND: Resistance to activated protein C (APC) is the most frequent cause of inherited thrombophilia. This phenomenon has been reported in 10-50% of selected patients with venous thromboembolism, a variation that might result from different degrees of selection in different reports. METHODS: We measured the APC sensitivity ratio in 494 frozen blood samples from unselected consecutive outpatients suspected of...
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