Article
Lack of Drosophila cytoskeletal tropomyosin affects head morphogenesis and the accumulation of oskar mRNA required for germ cell formation.
The EMBO journal - 15 Mar 1996
Tetzlaff M T, Jäckle H, Pankratz M J
Abstract excerpt
Drosophila encodes five muscle and one cytoskeletal isoform of the actin-binding protein tropomyosin. We have identified a lack-of-function mutation in the cytoskeletal isoform (cTmII). Zygotic mutant embryos show a defect in head morphogenesis, while embryos lacking maternal cTmII are defective...
Topics
- Animals
- Base Sequence
- Cytoskeleton
- Drosophila
- Drosophila Proteins
- Genes, Insect
- Germ Cells
- Head
- Immunohistochemistry
- Molecular Sequence Data
- Mutation
- Phenotype
- Protein Biosynthesis
- Proteins
- RNA, Messenger
- Tropomyosin