Article
The Brn-3a transcription factor induces neuronal process outgrowth and the coordinate expression of genes encoding synaptic proteins.
Molecular and cellular biology - 1 Jan 1997
Smith M D, Dawson S J, Latchman D S
Abstract excerpt
The Brn-3a POU family transcription factor is expressed only in posmitotic neurons in the central nervous system and identifies the first differentiated neurons to appear in the midbrain, hindbrain, and spinal cord during development. This factor is also induced when undifferentiated proliferatin...
Topics
- Animals
- Cell Differentiation
- DNA-Binding Proteins
- Ganglia, Spinal
- Gene Expression Regulation
- Genes
- Hybrid Cells
- Membrane Proteins
- Mice
- Mutation
- Nerve Tissue Proteins
- Neurites
- Neuroblastoma
- Neurons
- RNA, Messenger
- Rats
- Synaptosomal-Associated Protein 25
- Transcription Factor Brn-3