Article
Genetic complementation between replication-defective mutants of HIV-1 and SIVagm.
Archives of virology - 1 Jan 1996
Miura T, Shibata R, Adachi A, Kuwata T, Chen J, Jin M, Ido E, Hayami M
Abstract excerpt
To investigate the functional complementation of essential genes for virus growth between HIV-1 and SIVagm derived from African green monkeys, we co-transfected replication-defective molecular clones containing mutations in gag, pol, env, tat or rev, and monitored transient complementation by reverse transcriptase assay (RT), cytopathic effect (CPE) and immunofluorescence assay (IFA). The following results were...
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