Rapid complementation assays measuring replicative potential of human immunodeficiency virus type 1 envelope glycoprotein mutants.

doi:10.1128/JVI.64.5.2416-2420.1990

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Article

Rapid complementation assays measuring replicative potential of human immunodeficiency virus type 1 envelope glycoprotein mutants.

Journal of virology - 1 May 1990

Helseth E, Kowalski M, Gabuzda D, Olshevsky U, Haseltine W, Sodroski J

Abstract excerpt

Rapid assays which measure the ability of mutant human immunodeficiency virus type 1 envelope glycoproteins to mediate cell-free and/or cell-to-cell transmission of virus are described. By using these assays, envelope glycoprotein mutants with varying degrees of syncytium-forming ability were tes...

Topics

Animals
Cell Line
Chloramphenicol O-Acetyltransferase
Genetic Complementation Test
Giant Cells
HIV
Humans
Mutation
Plasmids
Transfection
Viral Envelope Proteins
Virus Replication

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