Article
Complementation of a deletion in the rubella virus p150 nonstructural protein by the viral capsid protein.
Journal of virology - 1 Sept 2003
Tzeng Wen-Pin, Frey Teryl K
Abstract excerpt
Rubella virus (RUB) replicons with an in-frame deletion of 507 nucleotides between two NotI sites in the P150 nonstructural protein (DeltaNotI) do not replicate (as detected by expression of a reporter gene encoded by the replicon) but can be amplified by wild-type helper virus (Tzeng et al., Virology 289:63-73, 2001). Surprisingly, virus with DeltaNotI was viable, and it was hypothesized that this was due to...
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