Article
Genetic instability of microsatellites in endometrial carcinoma.
Cancer research - 1 Nov 1993
Risinger J I, Berchuck A, Kohler M F, Watson P, Lynch H T, Boyd J
Abstract excerpt
Hereditary nonpolyposis colorectal cancer (HNPCC) is characterized by a familial predisposition to colorectal carcinoma and extracolonic cancers of the gastrointestinal, urological, and female reproductive tracts, notably the endometrium. A genetic locus for HPNCC was recently determined by linkage analysis to exist on chromosome 2p; both sporadic and HNPCC-associated colorectal carcinomas exhibit a "replication...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
