Article
Genetic instability of microsatellites in endometrial carcinoma.
Cancer research - 1 Nov 1993
Risinger J I, Berchuck A, Kohler M F, Watson P, Lynch H T, Boyd J
Abstract excerpt
Hereditary nonpolyposis colorectal cancer (HNPCC) is characterized by a familial predisposition to colorectal carcinoma and extracolonic cancers of the gastrointestinal, urological, and female reproductive tracts, notably the endometrium. A genetic locus for HPNCC was recently determined by linka...
Topics
- Adult
- Aged
- Aged, 80 and over
- Carcinoma, Endometrioid
- Chromosome Mapping
- Chromosomes, Human, Pair 2
- Colorectal Neoplasms
- Colorectal Neoplasms, Hereditary Nonpolyposis
- DNA, Satellite
- Female
- Humans
- Middle Aged
- Mutation
- Ovarian Neoplasms
- Polymerase Chain Reaction
- Repetitive Sequences, Nucleic Acid
