Array analysis of gene expression in connexin-43 null astrocytes.

Abstract excerpt

Connexin-43 (Cx43) is the most abundant gap junction protein in brain, where it is found primarily between astrocytes. Although the morphology of astrocytes from Cx43-null (knockout, KO) mice is similar to that of wild-type (WT) astrocytes, KO astrocytes exhibit reduced growth rate in culture. To evaluate the impact of deletion of Cx43 on other genes, including those encoding cell cycle proteins, we used DNA...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Apoptosis
• Share to Astrocytes
• Share to Cell Communication