Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Alpha 2-adrenergic agonists increase cellular lactate efflux.

Hypertension (Dallas, Tex. : 1979) - 1 May 1996

Lockette W, Kirkland K, Farrow S

Abstract excerpt

We reported previously that genetic polymorphisms of the alpha 2-adrenergic receptor are associated with hyperinsulinemia, diabetes mellitus, and hypertension in blacks. The evolutionary driving force for maintaining such deleterious mutations in the black population is unknown. Recognizing that vascular alpha 2-adrenergic receptors mediate cold-induced vasoconstriction and that temperature maintenance is a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Insulin
Share to Cells, Cultured
Share to Cerebrovascular Disorders

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Predisposition to Disease

Share to Muscle, Smooth, Vascular

Share to Rats, Inbred SHR

Share to Rats, Inbred WKY

Source

Identifiers

PMID: 8621203
DOI: 10.1161/01.hyp.27.5.1104

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Alpha 2-adrenergic agonists increase cellular lactate efflux.PMID 8621203Read ↗

Alpha 2-adrenergic receptor gene polymorphism and hypertension in blacks.Semantic proximity Read ↗

Altered beta-2 adrenergic receptor gene expression in human clinical hypertension.Semantic proximity Read ↗

Expression of altered alpha2-adrenergic phenotypic traits in normotensive humans at genetic risk of hereditary (essential) hypertension.Semantic proximity Read ↗

Sympathoneural and adrenomedullary functional effects of alpha2C-adrenoreceptor gene polymorphism in healthy humans.Semantic proximity Read ↗

Response to catecholamine stimulation of polymorphisms of the beta-1 and beta-2 adrenergic receptors.Semantic proximity Read ↗

Interactions between beta-2 adrenoceptor gene variation, cardiovascular control and dietary sodium in healthy young adults.Semantic proximity Read ↗

Ethnic and genetic determinants of cardiovascular response to the selective alpha 2-adrenoceptor agonist dexmedetomidine.Semantic proximity Read ↗

Alpha-adrenergic receptor gene polymorphisms and cardiovascular reactivity to stress in Black adolescents and young adults.Semantic proximity Read ↗

Beta-adrenergic receptor gene polymorphisms and cardiovascular reactivity to stress in Black adolescents and young adults.Semantic proximity Read ↗

beta2-adrenergic receptor polymorphisms at amino acid 16 differentially influence agonist-stimulated blood pressure and peripheral blood flow in normal individuals.Semantic proximity Read ↗

Interaction between cardiac sympathetic drive and heart rate in heart failure: modulation by adrenergic receptor genotype.Semantic proximity Read ↗

Impaired function of coronary BK(Ca) channels in metabolic syndrome.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.