Article
GAGA protein is essential for male germ cell development in Drosophila.
Genesis (New York, N.Y. : 2000) - 1 Aug 2014
Dorogova Natalia V, Fedorova Elena V, Bolobolova Elena Us, Ogienko Anna A, Baricheva Elina M
Abstract excerpt
The Drosophila Trithorax-like (Trl) gene encodes a GAGA factor which regulates a number of developmentally important genes. In this study, we identify a new function for Drosophila GAGA factor in male germ cell development. Trl mutants carrying strong hypomorphic alleles display loss of primordial germ cells during their migration in embryogenesis and severe disruption in mitochondria structure during early...
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