GAGA mediates the enhancer blocking activity of the eve promoter in the Drosophila embryo.

doi:10.1101/gad.12.21.3325

Back to search

Article

GAGA mediates the enhancer blocking activity of the eve promoter in the Drosophila embryo.

Genes & development - 1 Nov 1998

Ohtsuki S, Levine M

Abstract excerpt

Insulator DNAs and promoter competition regulate enhancer-promoter interactions within complex genetic loci. A transgenic embryo assay was used to obtain evidence that the Drosophila eve promoter possesses an insulator activity that can be uncoupled from the core elements that mediate competition...

Topics

Animals
Animals, Genetically Modified
Bacterial Proteins
DNA-Binding Proteins
Drosophila
Drosophila Proteins
Enhancer Elements, Genetic
Homeodomain Proteins
Mutation
Promoter Regions, Genetic
Repressor Proteins
TATA Box
Transcription Factors

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.