Article
GAGA mediates the enhancer blocking activity of the eve promoter in the Drosophila embryo.
Genes & development - 1 Nov 1998
Ohtsuki S, Levine M
Abstract excerpt
Insulator DNAs and promoter competition regulate enhancer-promoter interactions within complex genetic loci. A transgenic embryo assay was used to obtain evidence that the Drosophila eve promoter possesses an insulator activity that can be uncoupled from the core elements that mediate competition. The eve promoter contains an optimal TATA element and a GAGA sequence. The analysis of various chimeric promoters...
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