Characterization of a small supernumerary ring X chromosome by fluorescence in situ hybridization.

doi:10.1002/ajmg.1320470804

Back to search

Article

Characterization of a small supernumerary ring X chromosome by fluorescence in situ hybridization.

American journal of medical genetics - 1 Dec 1993

Duncan A M, Macdonald A, Brown C J, Wolff D, Willard H F, Sutton B

Abstract excerpt

We report on a male with mild learning disabilities who has a supernumerary marker chromosome. The marker chromosome was defined by fluorescence in situ hybridization as a ring X chromosome with breakpoints in the juxacentromeric region. Replication studies suggest that the ring X is late-replica...

Topics

Base Sequence
Child
DNA Primers
Dosage Compensation, Genetic
Humans
In Situ Hybridization, Fluorescence
Karyotyping
Male
Molecular Sequence Data
Phenotype
Ring Chromosomes
X Chromosome

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.