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Article

Arterial heparan sulfate proteoglycans inhibit vascular smooth muscle cell proliferation and phenotype change in vitro and neointimal formation in vivo.

Journal of vascular surgery - 1 Aug 1998

Bingley J A, Hayward I P, Campbell J H, Campbell G R

Abstract excerpt

PURPOSE: The aim of this study was to determine whether heparan sulfate proteoglycans (HSPGs) from the normal arterial wall inhibit neointimal formation after injury in vivo and smooth muscle cell (SMC) phenotype change and proliferation in vitro. METHODS: Arterial HSPGs were extracted from rabbi...

Topics

Animals
Carotid Arteries
Carotid Stenosis
Catheterization
Cell Division
DNA Replication
Fibromuscular Dysplasia
Heparan Sulfate Proteoglycans
Muscle, Smooth, Vascular
Phenotype
Rabbits
Tunica Intima

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 9719326
DOI: 10.1016/s0741-5214(98)70167-3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9719326-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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