Article
K-ras mutation analysis of residual liquid-based cytology specimens from endoscopic ultrasound-guided fine needle aspiration improves cell block diagnosis of pancreatic ductal adenocarcinoma.
PloS one - 1 Jan 2018
Sekita-Hatakeyama Yoko, Nishikawa Takeshi, Takeuchi Mao, Morita Kouhei, Takeda Maiko, Hatakeyama Kinta, Nakai Tokiko, Uchiyama Tomoko, Itami Hiroe, Fujii Tomomi, Mitoro Akira, Sho Masayuki, Ohbayashi Chiho
Abstract excerpt
BACKGROUND: Endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) technology is widely used for the diagnosis of pancreatic masses. However, in some cases, inadequate tissue volume or difficulty of morphological diagnosis are constraining factors for adequate cytopathological evaluation. K-ras mutation is the most frequently acquired genetic abnormality, occurring in approximately 90% of all patients with...
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