Article
Hereditary nonpolyposis colorectal cancer (Lynch syndrome). An updated review.
Cancer - 15 Sept 1996
Lynch H T, Smyrk T
Abstract excerpt
BACKGROUND: Hereditary nonpolyposis colorectal cancer (HNPCC) dates to Aldred Warthin's description of Family G a century ago. The phenotype features an excess of early onset colorectal carcinoma (CRC) with a propensity to involve the proximal colon, and a variety of extracolonic cancers, particularly carcinoma of the endometrium, ovary, stomach, small bowel, ureter, and renal pelvis. The recent discovery that...
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