Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Cytoskeletal control of myogenesis: a desmin null mutation blocks the myogenic pathway during embryonic stem cell differentiation.

Developmental biology - 1 Dec 1995

Weitzer G, Milner D J, Kim J U, Bradley A, Capetanaki Y

Abstract excerpt

A differentiating system based on embryonic stem (ES) cell-derived embryoid bodies (EBs) which recapitulates the in vivo cardiac, skeletal, and smooth muscle myogenesis of mouse embryos was developed and used to investigate the effects of the disruption of the desmin gene on muscle cell differentiation. Wild-type, heterozygous, and homozygous cell lines with the mutated desmin allele were evaluated. Skeletal...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Differentiation
Share to Cells, Cultured

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Muscle, Skeletal

Share to Mutation

Share to Recombination, Genetic

Share to Signal Transduction

Share to Stem Cells

Source

Identifiers

PMID: 8612961
DOI: 10.1006/dbio.1995.8070

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Cytoskeletal control of myogenesis: a desmin null mutation blocks the myogenic pathway during embryonic stem cell differentiation.PMID 8612961Read ↗

Amino-terminally truncated desmin rescues fusion of des(-/-) myoblasts but negatively affects cardiomyogenesis and smooth muscle development.Semantic proximity Read ↗

Knockout of zebrafish desmin genes does not cause skeletal muscle degeneration but alters calcium fluxSemantic proximity Read ↗

Knockout of zebrafish desmin genes does not cause skeletal muscle degeneration but alters calcium flux.Semantic proximity Read ↗

Desmin related disease: a matter of cell survival failure.Semantic proximity Read ↗

Desmin myopathy, a skeletal myopathy with cardiomyopathy caused by mutations in the desmin gene.Semantic proximity Read ↗

Desminopathies in muscle disease.Semantic proximity Read ↗

Stem cells and their derivatives can bypass the requirement of myocardin for smooth muscle gene expression.Semantic proximity Read ↗

Lack of desmin results in abortive muscle regeneration and modifications in synaptic structure.Semantic proximity Read ↗

Developmental Alterations in Heart Biomechanics and Skeletal Muscle Function in Desmin Mutants Suggest an Early Pathological Root for Desminopathies.Semantic proximity Read ↗

Desmin filaments and cardiac disease: establishing causality.Semantic proximity Read ↗

Mouse model of desmin-related cardiomyopathy.Semantic proximity Read ↗

[Desmin filaments and their disorganization associated with myofibrillar myopathies].Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.