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Article

Knockout of zebrafish desmin genes does not cause skeletal muscle degeneration but alters calcium flux.

Scientific reports - 5 Apr 2021

Kayman Kürekçi Gülsüm, Kural Mangit Ecem, Koyunlar Cansu, Unsal Seyda, Saglam Berk, Ergin Bora, Gizer Merve, Uyanik Ismail, Boustanabadimaralan Düz Niloufar, Korkusuz Petek, Talim Beril, Purali Nuhan, Hughes Simon M, Dincer Pervin R

Abstract excerpt

Desmin is a muscle-specific intermediate filament protein that has fundamental role in muscle structure and force transmission. Whereas human desmin protein is encoded by a single gene, two desmin paralogs (desma and desmb) exist in zebrafish. Desma and desmb show differential spatiotemporal expression during zebrafish embryonic and larval development, being similarly expressed in skeletal muscle until hatching,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 33820917
DOI: 10.1038/s41598-021-86974-w
PMCID: PMC8021586

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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