Article
Induction of apoptosis by the c-Myc helix-loop-helix/leucine zipper domain in mouse 3T3-L1 fibroblasts.
The Journal of biological chemistry - 1 Dec 1995
Kohlhuber F, Hermeking H, Graessmann A, Eick D
Abstract excerpt
The cellular proto-oncogene c-myc is involved in cell proliferation and transformation but is also implicated in the induction of programmed cell death (apoptosis). The c-Myc protein is a transcriptional activator with a carboxyl-terminal basic region/helix-loop-helix (HLH)/leucine zipper (LZ) do...
Topics
- 3T3 Cells
- Animals
- Apoptosis
- Base Sequence
- Basic Helix-Loop-Helix Leucine Zipper Transcription Factors
- Basic-Leucine Zipper Transcription Factors
- Blood
- DNA
- DNA Replication
- DNA-Binding Proteins
- Genes, Dominant
- Helix-Loop-Helix Motifs
- Leucine Zippers
- Mice
- Molecular Sequence Data
- Mutation
- Oligodeoxyribonucleotides
- Proto-Oncogene Proteins c-myc