Article
Determination and allelic allocation of seven nucleotide transitions within the arylamine N-acetyltransferase gene in the Polish population.
Clinical pharmacology and therapeutics - 1 Apr 1996
Mrozikiewicz P M, Cascorbi I, Brockmöller J, Roots I
Abstract excerpt
The frequency of various genotypes of arylamine N-acetyltransferase (NAT2) was investigated in 248 Polish unrelated children. Allele-specific polymerase chain reaction (PCR) was applied for mutation at 341 nucleotide (nt) of NAT2 coding sequence and PCR/restriction fragment length polymorphism fo...
Topics
- Adolescent
- Alleles
- Arylamine N-Acetyltransferase
- Base Sequence
- Child
- Child, Preschool
- Female
- Genotype
- Humans
- Male
- Molecular Sequence Data
- Nucleotides
- Point Mutation
- Poland
- Polymerase Chain Reaction
- Polymorphism, Restriction Fragment Length