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Article

Coloboma hyperactive mutant exhibits delayed neurobehavioral developmental milestones.

Brain research. Developmental brain research - 21 Nov 1995

Heyser C J, Wilson M C, Gold L H

Abstract excerpt

The coloboma mutation (Cm) is a neutron-irradiation induced gene deletion located on the distal portion of mouse chromosome 2. This deletion region includes a gene encoding the synaptic vesicle docking fusion protein, synaptosomal-associated protein of 25 kDa (SNAP-25). The resulting mutation is semi-dominant with heterozygote mice exhibiting a triad of phenotypic abnormalities that comprise profound spontaneous...

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PMID: 8612329
DOI: 10.1016/0165-3806(95)00130-6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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