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Article

Animal models of neurodevelopmental disorders with behavioral phenotypes.

Current opinion in psychiatry - 1 Mar 2021

Harris James C

Abstract excerpt

PURPOSE OF REVIEW: Genetic mutations in animals advance our understanding of disease mechanisms and treatments of neurodevelopmental disorders. Research with mutant mouse models is being extended to nonhuman primates whose brain development is closer to that of humans. This review summaries advances in mouse and nonhuman primate models. RECENT FINDINGS: Mutant mouse models recapitulate key symptoms in...

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PMID: 33395099
DOI: 10.1097/YCO.0000000000000675

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