Wocko, a neurological mutant generated in a transgenic mouse pedigree.

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Wocko, a neurological mutant generated in a transgenic mouse pedigree.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 1 Jun 1991

Crenshaw E B, Ryan A, Dillon S R, Kalla K, Rosenfeld M G

Abstract excerpt

Naturally occurring mutations involving the nervous system have provided virtually all of our current understanding of the genetic regulation of neural development (Caviness and Rakic, 1978). The difficulty of isolating the corresponding genes, however, has precluded a molecular analysis of these mutants. Insertional mutagenesis, induced by microinjection of DNA into fertilized ova to produce transgenic animals,...

Topics

Animals
Avian Sarcoma Viruses
Base Sequence
Female
Genes, src
Humans
Male
Mice
Mice, Neurologic Mutants
Mice, Transgenic
Molecular Sequence Data

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Oligonucleotide Probes

Phenotype

Polymerase Chain Reaction

Promoter Regions, Genetic

RNA, Messenger

Vasopressins

Source

Open in PubMed Open full text

Identifiers

PMID: 1646293
PMCID: PMC6575413

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1646293-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Wocko, a neurological mutant generated in a transgenic mouse pedigree.PMID 1646293Read ↗

Genetics of peripheral vestibular dysfunction: lessons from mutant mouse strains.Semantic proximity Read ↗

A new mouse insertional mutation that causes sensorineural deafness and vestibular defects.Semantic proximity Read ↗

Characterization of a new mouse mutant, flouncer, with a balance defect and inner ear malformation.Semantic proximity Read ↗

Stargazer (stg), new deafness mutant in the Zucker rat.Semantic proximity Read ↗

Genetic interaction between members of the Vangl family causes neural tube defects in mice.Semantic proximity Read ↗

Neuroepithelial defects of the inner ear in a new allele of the mouse mutation Ames waltzer.Semantic proximity Read ↗

Vestibular pathology in a new-mutant mouse.Semantic proximity Read ↗

New insights into behaviour using mouse ENU mutagenesis.Semantic proximity Read ↗

Identification and characterisation of spontaneous mutations causing deafness from a targeted knockout programme.Semantic proximity Read ↗

Optic, olfactory, and vestibular dysmorphogenesis in the homozygous mouse insertional mutant Tg9257.Semantic proximity Read ↗

The "No Phenotype" Challenge in Analyzing Mutant Mice.Semantic proximity Read ↗

A genetic screen for mutations that affect cranial nerve development in the mouse.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.