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Article

Screening for mutations at codon 717 of the amyloid precursor protein gene in Alzheimer's disease.

Psychiatry and clinical neurosciences - 1 Jun 1995

Dai X Y, Hattori M, Hirasawa H, Isse K, Ueki A, Nanko S

Abstract excerpt

Three kinds of missense mutation at codon 717 of amyloid precursor protein (APP) gene (Val --> Ile; Val --> Gly; Val --> Phe) were screened in 114 patients with familial and sporadic Alzheimer's disease (AD), using a rapid testing method for each Val --> Gly and Val --> Phe mutation and Goate's method for Val --> Ile mutation based on the polymerase chain reaction. Mutations were not found in the subjects,...

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Source

Identifiers

PMID: 8612192
DOI: 10.1111/j.1440-1819.1995.tb02224.x

Genes

APP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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