Screening for amyloid beta precursor protein codon 665, 670/671 and 717 mutations in Finnish patients with Alzheimer's disease.

doi:10.1016/0304-3940(96)12364-8

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Article

Screening for amyloid beta precursor protein codon 665, 670/671 and 717 mutations in Finnish patients with Alzheimer's disease.

Neuroscience letters - 16 Feb 1996

Helisalmi S, Mannermaa A, Lehtovirta M, Ryynänen M, Riekkinen P, Soininen H

Abstract excerpt

In this study, we screened for the amyloid beta precursor protein (APP) 665 (glutamic acid to aspartic acid), 670/671 (lysine to asparagine and methionine to leucine) and 717 (valine to isoleucine) mutations in 34 persons affected with familial Alzheimer's disease (AD) and 139 with sporadic AD, o...

Topics

Age of Onset
Aged
Alzheimer Disease
Amyloid beta-Protein Precursor
Diagnosis, Differential
Finland
Humans
Middle Aged
Mutation

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