Testing for mutations in exon 17 of the beta-amyloid precursor protein gene in Finnish Alzheimer patients and normal subjects.

doi:10.1007/BF02253439

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Article

Testing for mutations in exon 17 of the beta-amyloid precursor protein gene in Finnish Alzheimer patients and normal subjects.

Journal of neural transmission. Parkinson's disease and dementia section - 1 Jan 1994

Heinonen O, Kurvinen K, Soininen H, Koponen H, Syrjänen S, Riekkinen P J

Abstract excerpt

Mutations in the beta-amyloid precursor protein gene on chromosome 21 were shown to cause a small proportion of Alzheimer's disease. We studied the occurrence of the point mutations in exon 17 of the beta-amyloid precursor protein gene in a sample of Finnish familial Alzheimer patients and nondem...

Topics

Age of Onset
Aged
Alzheimer Disease
Amyloid beta-Protein Precursor
Exons
Female
Finland
Genes
Humans
Male
Middle Aged
Mutation

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