Article
p300 protein as a coactivator of GATA-5 in the transcription of cardiac-restricted atrial natriuretic factor gene.
The Journal of biological chemistry - 26 Nov 1999
Kakita T, Hasegawa K, Morimoto T, Kaburagi S, Wada H, Sasayama S
Abstract excerpt
A cellular target of adenovirus E1A oncoprotein, p300 is a transcriptional coactivator and a negative regulator of cellular proliferation. A previous study suggests that the p300 family is also involved in cell type-specific transcription in cardiac myocytes. However, nothing is known about which cardiac transcription factor(s) interact with and transactivate through these proteins. The transcription factors...
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