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Article

Induction of apoptosis by adenovirus type 5 E1A in rat cells requires a proliferation block.

Oncogene - 1 Apr 1994

Mymryk J S, Shire K, Bayley S T

Abstract excerpt

Infection with Ad5dl520EIB-, an adenovirus producing only the 243 residue E1A protein and lacking the E1B region, caused apoptosis in normal rat kidney (NRK) cells as judged by the production of nucleosomal DNA fragments. Apoptosis occurred only when the cells were growth-inhibited by cell-cell contacts in confluent cultures or by serum starvation and not when they were actively growing. In uninfected cultures,...

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Source

Identifiers

PMID: 8134121

Genes

NRK

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Induction of apoptosis by adenovirus type 5 E1A in rat cells requires a proliferation block.PMID 8134121Read ↗

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