Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Primary mediastinal (thymic) B-cell lymphoma is characterized by gains of chromosomal material including 9p and amplification of the REL gene

15 Feb 1996

Abstract excerpt

Primary mediastinal (thymic) B-cell lymphoma is a high-grade non-Hodgkin's lymphoma with unique features. By using comparative genomic hybridization and interphase cytogenetics, 26 tumors were analyzed to identify genomic imbalances. Gains of chromosomal material were much more frequent than losses (110 v 10) and involved chromosomes 9p, 12q, and Xq (31% to 50%). Interestingly, gain of Xq coincided with gain of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chronic Lymphocytic Leukemia Research
Share to CNS Lymphoma Diagnosis and Treatment
Share to Lymphoma Diagnosis and Treatment

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 8608249
DOI: 10.1182/blood.v87.4.1571.bloodjournal8741571

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Primary mediastinal (thymic) B-cell lymphoma is characterized by gains of chromosomal material including 9p and amplification of the REL genePMID 8608249Read ↗

Gain of chromosome arm 9p is characteristic of primary mediastinal b-cell lymphoma (MBL): Comprehensive molecular cytogenetic analysis and presentation of a novel MBL cell lineSemantic proximity Read ↗

Similar patterns of genomic alterations characterize primary mediastinal large-B-cell lymphoma and diffuse large-B-cell lymphoma.Semantic proximity Read ↗

Hodgkin's lymphoma cell lines are characterized by frequent aberrations on chromosomes 2p and 9p including <i>REL</i> and <i>JAK2</i>Semantic proximity Read ↗

REL proto-oncogene is frequently amplified in extranodal diffuse large cell lymphomaSemantic proximity Read ↗

Alteration of chromosome arm 6p is characteristic of primary mediastinal B-cell lymphoma, as identified by genome-wide allelotyping.Semantic proximity Read ↗

The t(9;14)(p13;q32) chromosomal translocation associated with lymphoplasmacytoid lymphoma involves the PAX-5 geneSemantic proximity Read ↗

Concurrent activation of MYC and BCL2 in B cell non-Hodgkin lymphoma cell lines by translocation of both oncogenes to the same immunoglobulin heavy chain locus.Semantic proximity Read ↗

Molecular features of primary mediastinal B-cell lymphoma: involvement of p16INK4A, p53 and c-myc.Semantic proximity Read ↗

Genetic pathway to recurrent chromosome translocations in murine lymphoma involves V(D)J recombinaseSemantic proximity Read ↗

Molecular characterization of the t(3;9) associated with immortalization in the MCF10A cell line.Semantic proximity Read ↗

Genetic alterations in primary breast cancers and their metastases: Direct comparison using modified comparative genomic hybridizationSemantic proximity Read ↗

Chromosome 3 imbalances are the most frequent aberration found in non-small cell lung carcinoma.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.