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Article

REL proto-oncogene is frequently amplified in extranodal diffuse large cell lymphoma

1 Jan 1996

Abstract excerpt

Comparative genomic hybridization (CGH) analysis of DNA extracted from a diffuse lymphoma with a large cell component (DLLC) that displayed double minute chromosomes upon conventional karyotypic analysis indicated overt amplification of DNA sequences derived from the 2p13-15 region. Southern blot analysis of this tumor DNA with a cDNA probe for the proto-oncogene REL, previously mapped to 2p14-15, indicated a...

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Identifiers

PMID: 8547649
DOI: 10.1182/blood.v87.1.25.25

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