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Article

Molecular characterization of the t(3;9) associated with immortalization in the MCF10A cell line.

Cancer genetics and cytogenetics - 1 Nov 2005

Cowell John K, LaDuca Jeffrey, Rossi Michael R, Burkhardt Tania, Nowak Norma J, Matsui Sei-ichi

Abstract excerpt

The t(3;9)(p14;p21) in the MCF10A human mammary gland epithelial cell line was the single cytogenetic event that accompanied the transition from primary culture to immortalized cell line, suggesting that it is related to the development of the immortalization phenotype. To study the molecular consequences of the breakpoints in this rearrangement, we used a combination of fluorescence in situ hybridization (FISH)...

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Source

Identifiers

PMID: 16271952
DOI: 10.1016/j.cancergencyto.2005.04.019

Genes

TAFA1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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